PROGRAM

S1-1

Multiple functions of human amnion cells and amnion-derived stem cells.

Norio SAKURAGAWA1 and Yasunobu YOKOYAMA2 (1Department of Regenerative Medicine, Toho University School of Medicine, 2Department of Customer, Service, SRL, Inc.)

S1-2

Regulation of multipotentiality of muscle stem cells.

Naohiro HASHIMOTO (Stem Cell Research Unit, Mitsubishi Kagaku Institute of Life Sciences)

S1-3

Analysis of hematopoietic microenvironment by bone marrow stromal cell lines.

Masuo OBINATA (Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan)

S1-4

Regulation of cellular function by extracellular matrix molecules.

Kaoru MIYAZAKI (Kihara Institute for Biological Research, Yokohama City University)

S1-5

Molecular mechanism of atherosclerosis induced by lysophospholipids.

Kenji SOBUE (Department of Neuroscience, Osaka University Graduate School of Medicine)

S1-6

Isolation and characterization of genes in an attempt to understand regulatory mechanisms underlying cellular plasticity (EMT and phenotypic conversion of connective tissue cells).

Motoko SHIBANUMA (Department of Microbiology, Showa University, School of Pharmaceutical Sciences, Tokyo, Japan)

S2-1

Dream and Reality in business development of life science.

Mitsuru MIYATA (Emeging Technology Information Center, Nikkei Business Publications, Inc.)

S2-2

Potential and issue of business using human tissues - from the viewpoint of bio-venture capital.

Hiroshi GUSIMA (BIOFRONTIER PARTNERS)

S2-3

Patent Strategy and Business Strategy.

Kazuya KAWAMOTO (Shimizu Patent Office)

S2-4

Ownership of human embryonic stem cells and their effective application for research.

Koichi SUMIKURA (National Graduate Institute for Policy Studies)

S2-5

Business strategy of an R&D-based bio-venture.

Toshio SOFUNI (NovusGene Inc., Tokyo, Japan)

S2-6

Adoptive immunotherapy and cancer vaccine.

Tadao OHNO (Cell-Medicine, Inc., Ushiku, Japan)

AW-1

Effect of dexamethasone on urokinase-type plasminogen activator induced by inflammatory cytokines in human lung microvascular endothelial cells.

Katsuyuki KOBAYASHI, Kimiko TAKAHASHI, Hiroyuki NAKAMURA and Takeshi MATSUOKA (The Fifth Department of Internal Medicine, Tokyo Medical University, Ibaraki, Japan)

AW-2

Uni-axial stretch regulates intracellular localization of Hic-5, which is expressed in smooth muscle cells in vivo.

Shuri KANEYAMA, Kiyoshi NOSE and Motoko SHIBANUMA (Department of Microbiology, Showa University School of Pharmaceutical Sciences, Tokyo, Japan)

AW-3

Activin A induces craniofacial cartilage from undifferentiated Xenopus ectoderm in vitro.

Yasuto FUKUI1, Miho FURUE2, Yasufumi MYOISHI1, Makoto ASASHIMA3,4 and Tetsuji OKAMOTO1 (1Mol. Oral Med. & Maxillofacial Surg., Div. of Frontier Med. Sci., Graduate Scho. of Biomed. Sciences, Hiroshima Univ., 2Dept. of Biochemistry and Mol. Biol., Kanagawa Dental College, 3Japan Science and Technology Corporation, 4Dept. of Life Sciences (Biology), Graduate School of Arts and Sciences, The University of Tokyo)

O1-1

Attempt to make a "Movie Factory": Observation on the living cells.

Hideyuki TANABE1, Maki HOJO1, Miharu KUREMATSU1,2, Runa YASUDA1 and Hiroshi MIZUSAWA1 (1Cell Bank Laboratory, Division of Genetics and Mutagenesis, National Institute of Health Sciences, Tokyo, 2Japan Health Sciences Foundation)

O1-2

Establishment and culture of bovine embryonic stem-like cells using serum-free medium and feeder-free culture system.

Yutaka SENDAI, Shoko YAMASHITA, Masayuki KACCHI, Isao BITOU and Hiroyoshi HOSHI (Research Institute for the Functional Peptides)

O1-3

High density 3-dimensional culture of an immortalized human hepatocyte line (OUMS-29) in a radial flow bioreactor.

Ichiro AKIYAMA1, Masahiro MIYAZAKI1, Takuro MASAKA1, Masaaki MORI2, Masakiyo HOSOKAWA3, Seishi NAGAMORI4 and Nam-ho HUH1 (1Dept. Cell Biol., Okayama Univ. Grad. Sch. Med. Dent., 2v acul. Health Welf. Sci., Okayama Prefect. Univ., 3Lab. Biochem. Pharmacol. Toxicol., Grad. Sch. Pharmaceut. Sci., Chiba Univ. , 4Dept. General Med., Kyorin Univ. Sch. Med.)

O1-4

Relationship between amplifying STR-PCR peaks and changes of chromosome compositions after long-term cultivation: Analysis of HeLa AG clones by FISH.

Maki HOJO1, Runa YASUDA1, Hideyuki TANABE1, Yoko TAKADA1, Miharu KUREMATSU1,2, Tohru MASUI1 and Hiroshi MIZUSAWA1 (1Cell Bank Laboratory, Division of Genetics and Mutagenesis, National Institute of Health Sciences, Tokyo, 2Japan Health Sciences Foundation)

O1-5

Transition of tartrate-resistant acidphosphatase (TRACP) isozymes in rat.

Yoshihiko IGARASHI1, Ken-ichi MANAKA2, Samon SHIMIZU1 and Shigeru MATSUZAKI1 (1Department of Biochemistry, Dokkyo University School of Medicine, 2Institute for Medical Science, Dokkyo University School of Medicine)

O1-6

Expression of Myosin Heavy Chain of Myoblasts derived from Double-Muscled Japanese shorthorn cattle (DCMB).

Shinichiro HAYASHI1, Hisashi ASO1, Kouichi WATANABE1, Koichi CHIKUNI2, Toshiyuki SUZUKI3, Kyouhei OZUTSUMI2 Takahiro YAMAGUCHI1(1Laboratory of @Functional Morphology, Department of Animal Production Science, Division of Biological Resource Sciences, Graduate School of Agriculture Science, Tohoku University, Sendai, Japan, 2Department of Animal Products, National Institute of Livestock and Grassland Science, 3IARC, Animal Industry Research Institute)

O1-7

High-efficiency gene targeting in a human pre-B cell line.

Sairei SO and Hideki KOYAMA (Kihara Institute for Biological Research, Graduate School of Science, Yokohama City University, Yokohama, Japan)

O1-8

Analysis of gene function in testis by transgenic mice using Cre-loxP system.

Satoru ARATA1, Tatsuo KIDO2, Ryusuke SUZUKI2, Tomohiko HOSONO1, Toshio KUROKI3 and Seiji SHIODA 2 (1Center for Biotechnology, Showa University, Tokyo, Japan, 2Department of Anatomy, Showa University School of Medicine, Tokyo, Japan, 3Gifu University, Gifu, Japan)

O1-9

Analysis of the X-ray response in normal human keratinocytes using DNA chip.

Manabu KOIKE , Yasuharu NINOMIYA, Tomoe SHIOMI, Kaori OHNO and Aki KOIDE (Radiation Hazards Research Group, NIRS, Chiba, Japan)

O1-10

Effect of fixation and pretreatments on the immunostaining of keratins in skin.

Tomoe SHIOMI and Manabu KOIKE (Radiation Hazards Research Group, NIRS, Chiba, Japan)

O1-11

The histological study of tetrabromobisphenol A as a flame retardant on cultured rat embryos.

Masaharu AKITA1, Shigekazu SHIMIZU2, Yoshihiro NOZAKI2 Atsushi YOKOYAMA3 and Yukiaki KURODA4 (1Kamakura Women's University, Kanagawa, Japan, 2Fuji Biomedix Co. Ltd., 3Kanagawa Life Science Research Laboratory, 4National Institute of Genetics)

O1-12

Novel method for the detection of Mycoplasma/Acholeplasma by real-time PCR.

Yoko ISHIKAWA1, Takaharu KOZAKAI2, Hatsue MORITA1, Kaname SAIDA2, Yasuhiko KOMATSU1, Syuichi OKA1 and Yoshinori MASUO1,3 (1International Patent Organism Depositary, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan, 2Institute for Biological Resources and Functions, AIST, Tsukuba, Japan, 3NEDO, Tokyo, Japan)

O1-13

Development of video tape and documents for supporting patient understanding at tissue donation to governmental cell bank (JCRB).

Tohru MASUI1, Yoko TAKADA1, Hiroshi MIZUSAWA1, Hideki TANABE1, Miharu KUREMATSU1,2, Maki HOUJYOU1 Runa YASUDA1, Makoto HAYASHI1 (1The National Institute of Health Sciences, Department of Genetics and Mutagenesis, Cell Bank, 2Human Health Science Foundation)

O2-1

Application of telomerase for regenerating edicine.

Hidetoshi TAHARA and Toshinori IDE (Department of Cellular and Molecular Biology, Graduated School of Biomedical Sciences, Hiroshima University)

O2-2

Isolation and characterization of life-extended human osteoblasts.

Naoki ARAMAKI, Yoshifumi OHMAE, Kumiko ANNO, Hidetoshi TAHARA and Toshinori IDE (Graduated School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan)

O2-3

Establishment of immortalized cell line in calf oviduct epithelial cells.

Ken MURATA1,2, Sayuri KOIZUMI1,2, Kei HANZAWA1 and Sigeru YASUMOTO2 (1 Graduate School of Agriculture, Tokyo Univ. of Agriculture, Kanagawa, Japan, 2Mol. Cell. Biol., Kanagawa Cancer Ctr. Res. Inst., Kanagawa, Japan)

O2-4

Mouse Immortalized Hepatic Cells and IF3 gene.

Hiroshi MANO1 Haruka MAEHASHI2 Masahiro WADA1 Tomokazu MATSUURA3 (1Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Science, Josai University, Saitama, Japan, 2Department of Biochemistry, The Jikei University School of Medicine, Tokyo, Japan, 3Department of Laboratory Medicine, The Jikei University School of Medicine, Tokyo, Japan)

O2-5

Long-term culture of rat bone marrow derived hepatocytes.

Masahiro MIYAZAKI, Takuro MASAKA, Ichiro AKIYAMA and Nam-ho HUH (Department of Cell Biology, Okayama University Graduate School of Medicine and Dentistry)

O2-6

Induction of GI tract-like structure from mouse ES cell.

Katsuhiko ISHIZAKI1, Masaki KUWAHARA2, Shigeko TORIHASHI2, Yoshiakira KANAI3 and Takahiro KUNISADA1 (1Department of Tissue and Organ Development, Regeneration and Advanced Medical Science, Gifu University Graduate School of Medicine, Gifu, Japan, 2Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine, Aichi, Japan, 3Department of Veterinary Anatomy, Veterinary Medical Science/Animal Resource Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan)

O2-7

Differentiation of human bone marrow stroma cells into neuronal cells.

Tohru MARUNOUCHI, Shinya TOBA, Mahito OHKUMA, Hidehiko AKIYAMA and Nobuhiko MARUNOUCHI (Division of Cell Biology, Institute for Comprehensive Medical Science, Fujita-Health University Nagoya, Japan)

O2-8

Role of Vascular Endothelial Growth Factor -VEGF Receptor System in the Migration of Human Melanoma Cell Lines.

Koh-ichi KOIZUMI, Yasutaka HAYASHIDO, Yukio YOSHIOKA, Tomoaki SHINTANI, Tomoaki HAMANA, Hisakata KITANO, Yasushi OCHI and Tetsuji OKAMOTO (Department of Molecular Oral Medicine and Maxillofacial Surgery, Division of Frontier Medical Science, Graduate School of Biomedical sciences, Hiroshima University)

O2-9

Participation of integrin v in invasive growth of oral squamous cell carcinoma cells.

Hisataka KITANO, Yasutaka HAYASHIDO, Yukio YOSHIOKA, Hoh-ichi KOIZUMI, Tomoaki HAMANA and Tetsuji OKAMOTO (Department of Molecular Oral Medicine and Maxillofacial Surgery, Division of Frontier Medical Science, Graduate School of Biomedical Sciences Hiroshima University, Hiroshima, Japan)

O2-10

Molecular mechanisms of the acquiring malignant phenotype by epithelial-mesenchymal transition in squamous cell carcinoma.

asayuki TAKI, Nobuyuki KAMATA, Kazuhiro YOKOYAMA and Masaru NAGAYAMA (First Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Tokushima, Tokushima, Japan)

O2-11

Transcriptional regulation of angiogenesis-related angiopoietin-2.

Yasuhiro HASEGAWA, Mayumi ABE, Tohru YAMAZAKI, Kazuhide TERUYAMA and Yasufumi SATOU (Department of Vascular Biology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan)

O2-12

Production of urokinase-type plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1) by human lung microvascular endothelial cells and fibroblasts.

Kimiko TAKAHASHI, Katsuyuki KOBAYASHI, Osamu WATANABE, Koji KISHI and Takeshi MATSUOKA (Fifth Dept. of Internal Medicine, Tokyo Medical University)